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Vitamin B 12 deficiency symptoms may include: strange sensations, numbness, or tingling in the hands, legs, or feet difficulty walking (staggering, balance problems) anemia a swollen, inflamed tongue difficulty thinking and reasoning (cognitive difficulties), or memory loss weakness fatigue While an experienced physician may notice the symptoms and be able to detect a vitamin B 12 deficiency with a good interview and physical exam, a blood test is needed to confirm the condition

The peptide binds copper with extraordinarily high affinity (pK = 16.44), which is roughly 10 million times higher than other tripeptides and comparable to albumins copper binding

Vitamin B12 is naturally present in foods such as meat, fish, and dairy, where it binds to protein and is dissociated by gastric acid during digestion, enabling it to be taken into circulation

The treatment plans offered by Eric Nager, M.D