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demonstrated that the amount of NCOA4 depends on whether it interacts with the HERC2 protein

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Trazodone is also a 3A4 substrate, and so giving it with 3A4 inhibitors can heighten and prolong the sedation

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The TEV protease itself, with various mutations used to increase its stability activity, can be readily purified using plasmids found in this paper (available at Addgene)

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