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6.2 Systemic metabolism: conjugation and deconjugation Dietary polyphenols and microbial metabolites of procyanidins typically undergo a phase II metabolism in enterocytes and liver cells to form glucuronic acid, sulfate, and methyl conjugates (Figure 3) (27, 41, 73, 82, 83)

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Gclc is required for T cell-independent and -dependent B cell immune responses Next, we aimed to understand how the metabolic perturbations caused by B cell-specific Gclc ablation impinge on immune responses and in particular how the impaired mitochondrial metabolism affects the antibody response

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10.1021/acs.langmuir.9b01325 41 LiZ.LiD.LiQ.LuoC.LiJ.KouL.et al

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