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While we have shown that plasma proteomic organ aging models are distinct from previous proteomics models, clinical chemistry-based models and imaging-based models, future studies should assess how proteomic organ aging relates to other molecular measures of aging and disease such as methylation aging clocks and disease-specific prediction models

Besides, roFPs under physiological conditions are only sensitive to oxidative stress but not to any reductive stress because they completely transition to a fully reduced state once in the cytosol

Insights from these studies may pave the way for new formulations and delivery methods that optimize results

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