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doi: 10.1007/s00018-018-2943-4 4 AdnanS.NelsonJ

In individuals with IBD, proinflammatory cytokines downregulate OCTN2 through the PPAR/RXR pathway, resulting in reduced carnitine uptake by intestinal epithelial cells that leads to the dysfunction of intestinal regeneration and repair and further deterioration of IBD [232]

These inherent phospholipids strengthen cell membrane architecture, promoting optimal cellular function for absorbing vital nutrients and excreting cellular waste and environmental toxins (7)

In healthy adults, the microbiome, even at the level of strains, is relatively stable over many years (162)