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There appears to be a synergistic effect on modulation of alcohol and ingestion of phenytoin in incrementing serum GT levels

Oncotarget 8, 81649

Studies have highlighted the role of persistent fibrosis in aged tissues, where myofibroblasts in injured tissues of aged mice acquire a sustained senescent and apoptosis-resistant phenotype, exacerbating fibrosis (Hecker et al., 2014)