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207 As we know, most AMPs are membrane activity peptides, and that the enhanced positive charges of AMPs usually lead to higher activity, likely because the enhanced positive charges of AMPs result in increased affinity to the negatively charged cancer cell membranes

Furthermore, to validate uricosuric efficacy in animals exhibiting a high uric acid phenotype, the dual-gene edited composite model ( Uox KO/huURAT1 ) is highly recommended to obtain the most clinically translatable data