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Dual GLP1 and GIP agonists Tirzepatide is a once weekly, subcutaneous, unimolecular dual RA (GLP-1 and GIP) which has comparable GIP receptor binding affinity to native GIP and 5 times lower GLP-1 receptor affinity than that of native GLP-1

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In preclinical models these pathways translate into neuroprotection against amyloid-beta toxicity by preserving mitochondrial membrane potential and blocking apoptosis [3] , and into metabolic effects centrally-mediated improvements in insulin sensitivity and lower blood glucose in rodent studies [2]

The recommended serving size is one capsule per day. Many NMN supplements on our list require at least two capsules per serving size, so we love that this product supplies a clinical dose in one pill