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Methods: This is a cross-sectional study based on the Maule cohort (MAUCO)

Babault N, Allali-hassani A, Li F, Fan J, Yue A, Ju K, Liu F, VedadI M, Liu J, Jin J (2018) Discovery of bisubstrate inhibitors of nicotinamide N -methyltransferase (NNMT)

first proposed a dual nanosystem containing a nanomaterial component (gold nanorods) and a genetic component (temperature-sensitive transient receptor potential [TRP] channels)

Nevertheless, the association between low levels of ROS and the generation of double-strand breaks remains a topic of debate, partly owing to methodological challenges, such as those encountered with the neutral Comet assay and the use of nonspecific biomarkers for double-strand breaks, such as gamma-H2AX, an early cellular response to the induction of DNA double-strand breaks