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FEBS Lett 237:150154

3) HNE had no effect on IL-1 secretion mediated by AIM2 and NLRC4 inflammasome activation, although NLRP3, NLRC4, and AIM2 inflammasomes share the adaptor protein ASC and effector protein caspase-1

McNamara DA, Brophy S, Hyland JM

49 ER stress and glaucoma Glaucoma is a heterogeneous group of diseases characterized by cupping of the optic nerve head and visual-field damage, which may result in irreversible blindness and is the second leading cause of irreversible blindness worldwide