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bioRxiv 10.1101/2020.02.20.958579

K.et al (2018)

Additionally, butyrate regulates gut immune cell function by inhibiting histone deacetylase (HDAC) activity, promoting the differentiation of Treg, and suppressing the release of pro-inflammatory cytokines such as IL-6 and TNF-, thereby alleviating intestinal inflammation [439, 440]