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The Tier 2 supplements include: Vitamin B12 (when serum B12 is below my threshold) Folate (when serum folate or red cell folate is low) Iron (when iron studies show depletion or frank anaemia) Vitamin A (when serum retinol is low) Thiamine (B1) (when whole blood thiamine is low) Vitamin B6 (when PLP is low) Calcium citrate (guided by calcium, vitamin D, and clinical context) Selenium (when selenium is low, more common in post-bariatric patients) The principle is that I do not add these reflexively

SSRI use was significantly associated with a 0.7560-point lower PSQI score, indicating better sleep quality, compared to non-use

Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action