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(2016) 2(10):e1601273

Therefore, in patients with insulin resistance but without acute inflammatory conditions, severe alcohol abuse or poorly controlled diabetes mellitus, serum levels of ferritin are mainly determined by dysregulation of iron metabolism and next by the severity of insulin resistance

M., Ren, Z., Morciano, G., Perrone, M., Patalas-Krawczyk, P., Borchard, S., Jdrak, P., Pierzynowska, K., Szymaski, J., Wang, D

We have validated that this TYR-catalyzed prodrug activation approach could effectively retain the intracellular drug concentration to resensitize the drug-resistant melanoma cells to chemotherapeutics both in vitro and in vivo