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Summary: Vitamin B12 deficiency symptoms include persistent fatigue, pins and needles in hands and feet, memory problems, breathlessness, balance difficulties, and mood changes, with neurological damage possible even before anaemia develops

The mechanism of decreased lipid turnover with aging may be due to decreased sympathetic tone (236)

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Full-length growth hormone produces fat loss but also elevates IGF-1 (with implications for cell proliferation and aging), worsens insulin sensitivity and elevates blood glucose (problematic for diabetics and pre-diabetics), promotes muscle growth and protein synthesis (which may be desired or unwanted depending on goals), causes fluid retention and edema in many users, and requires careful medical monitoring with regular blood work