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According to the incidence, prevalence, and social impact up to 349.2 million individuals were affected by major neurological disorders worldwide (Ding et al., 2022

doi: 10.1152/japplphysiol.00305.2005

Irradiation with a single dose of 5 Gy led to a pronounced and sustained reduction of GSH that was still visible 12 h after irradiation, whereas GSH levels of irradiated TrC1 AKT-E17K cells at 12 h after irradiation were similar to untreated control cells ( Figure 1B )

However, it is important to acknowledge that this superiority was not consistent across all biochemical parameters: markers such as SOD, CAT, MDA, IL-1, SLC7A11, and Nrf2 did not differ significantly between the combination and TMZ alone