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Similarly, 600 mg LA/day, i.v., for 3 weeks showed no adverse effects [58], and 1800 mg LA/day, p.o., for 6 months was also safe [59]

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Enzyme-linked immunosorbent assay (ELISA) was performed to detect serum levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), as well as the levels of GSH, tumor necrosis factor, interleukin (IL) 10, integrin alpha M, IL1B, malondialdehyde, nicotinamide adenine dinucleotide phosphate oxidase 4, and superoxide dismutases in hepatocyte homogenates

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