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Lipoperoxyl radicals have significant oxidative potential, they can further initiate the seizure of hydrogen from the neighbouring unsaturated fatty acid, by which lipid peroxidation enters the phase of propagation and autooxidaton, resulting in formation of lipid hydroperoxyde (LOOH) and new lipid radicals (L )

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For many women, skin changes become more noticeable during perimenopause and menopause as antioxidant defenses decline alongside estrogen