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However, some studies have shown inadequate levels of copper and manganese in the hippocampus in patients with MTLE and hippocampus sclerosis (MTLS-HS), while iron levels remain unaltered ( In summary, abnormal iron metabolism and distribution in the brain of epileptic patients might be one of the reasons for the occurrence and development of epilepsy

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Alogliptin affects several signaling mechanisms that enabled researchers to exploit its effects on pathologies related to other organ systems [9]

Further, identifying epigenetic changes that occur as a consequence of sleep deprivation could lead to the development of novel therapies to treat sleep-related disorders and the cognitive deficits associated with sleep loss