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One of the most intriguing aspects of methylene blue is its redox activity

Using less water will result in a more concentrated solution (more mcg per unit), while more water will make it more dilute.

(PubMed) Reid ME, Duffield-Lillico AJ, Slate E, et al

Similarly, in traditional Western herbal medicine, licorice is classified as an adaptogenic plant, and used as an adrenal tonic to help improve resilience against the negative physical, mental and emotional impacts of acute or chronic stress