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Animal studies show substantial evidence across stroke models (full functional recovery in spatial memory, motor coordination, balance), Parkinsons models (protection of dopaminergic neurons, near-complete prevention of mortality), multiple sclerosis models (significantly less brain damage), and traumatic brain injury (reduced hemorrhage and edema)

Transcriptome-wide analysis of human liver reveals age-related differences in the expression of select functional gene clusters and evidence for a PPP1R10-governed aging cascade

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