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Surgical treatment remains the only therapy for MSL

These resistance mechanisms reduce intracellular drug accumulation and undermine treatment efficacy, posing a major challenge in the clinical management of fungal infections

& Akashi, K

Nevertheless, macrophage cholesterol efflux to HDL reduces inflammation and the atherosclerotic burden, and is the first step in reverse cholesterol transport (RCT) (Figure 10) (685-687)