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"Conversion of dietary phylloquinone to tissue menaquinone-4 in rats is not dependent on gut bacteria"

A 2016 systematic review of clinical evidence on newer vs older diabetes medications supports metformin as 1st-line therapy for type 2 diabetes given its relative safety & beneficial effect to lower HbA1c, absence of weight gain, and reduced cardiovascular mortality (Maruthur et al, 2016)

This article reports a demonstration of the direct screening of l -DNA aptamers from mirror-image nucleic acid libraries using mirror-image DNA polymerases