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The diluent is Bacteriostatic Water for Injection, USP containing 0.9% Benzyl Alcohol added as an antimicrobial preservative

As a biguanide antihyperglycemic agent, metformin works primarily by decreasing hepatic glucose production, reducing intestinal absorption of glucose, and improving insulin sensitivity in peripheral tissues

While higher doses (particularly 54 mg) showed some increase in gastrointestinal-related events, these remained mild to moderate in severity and did not result in treatment discontinuation

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