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Proangiogenic substances like VEGF and PDGF, which suppress apoptosis and encourage cell proliferation, motility, and survival, are known to contribute to angiogenesis

Its primary actions include: Increasing slow-wave (delta) sleep the deepest, most physically restorative sleep stage Modulating corticotropin-releasing hormone (CRH) reducing the HPA axis signalling that keeps cortisol elevated Influencing LH and somatostatin release both relevant to testosterone and growth hormone secretion Antioxidant activity preclinical data suggests DSIP has direct free-radical scavenging properties (3) Thermoregulatory effects potentially lowering basal body temperature in a manner consistent with natural sleep onset The net effect is not sedation

Dosage and frequency depend on individual health needs

10.1002/14651858.CD002967 111 SalvatoreT.GalieroR.CaturanoA.VetranoE.RinaldiL.CovielloF.et al (2021)