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However, the mechanism beneath the effect of GSH depletion-induced oxidative stress in RPE cells and the subsequent RPE damage is not well established

Issues such as unhealthy dietary patterns, physical inactivity and sedentary lifestyles, harmful advertising practices targeting children related to unhealthy foods, limited access to healthy food outlets in low income or rural communities are among the factors contributing to rising rates of obesity around the world

In future studies, researchers should optimize the dose of N-Acetyl Cysteine, length of the supplementation, chronicity of illness, and other factors