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Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE

Further, AMPK has been reported to be an upstream activator of NRF2 85

[DOI] [PubMed] [Google Scholar] Tavares L.P., Garcia C.C., Machado M.G., Queiroz-Junior C.M., Barthelemy A., Trottein F., Siqueira M.M., Brandolini L., Allegretti M., Machado A.M., De Sousa L.P., Teixeira M.M

It serves as a foundational model for the molecular design of target-sensing inhibitors without requiring detailed fine-tuning with target-specific data