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Under FDA regulations, compounding of approved drugs is generally restricted to patient-specific prescriptions from licensed pharmacies, not bulk manufacturing of "research chemicals." This is an important distinction from research peptides that have no FDA approval those compounds exist in a different regulatory category entirely

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Lilly has demonstrated their ability to bring complex peptide therapies through the regulatory process, and their phase 3 TRIUMPH trial program for retatrutide includes multiple studies across different patient populations

Interestingly, dDIA yields similar number of phosphopeptides and sites as DDA and DIA with the community library