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Here, we show that MOTS-c, a peptide encoded in the mitochondrial genome, translocates to the nucleus and regulates nuclear gene expression following metabolic stress in a 5'-adenosine monophosphate-activated protein kinase (AMPK)-dependent manner

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It is commonly used as part of hormone replacement therapy (HRT) for individuals looking to support healthy aging, improve muscle mass, and enhance overall well-being

Id switched from vitamin B12 injections to methylcobalamin B12 lozenges some years earlier ~ methylcobalamin lozenges are effective, without the discomfort of the needles