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Indeed, SLC6A14 is overexpressed in colon, cervical, ER-positive breast, and pancreatic cancer cells and is associated with their proliferation 101,102,103,104

Notably, ferroptosis is characterized by lipid ROS accumulation (Guo et al., 2022) Therefore, we speculate that ferroptosis of OA chondrocytes may release a large amount of ROS into the blood circulation, increasing the level of serum oxidative stress, thereby disturbing the intestinal homeostasis and further exacerbating the pathological process of OA

Necrostatin-1 prevents ferroptosis in a RIPK1- and Ido-independent manner in hepatocellular carcinoma

And I don't do that