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In addition, recent research has shown that the gut microbiota can ferment indigestible carbohydrates, like dietary fiber, producing succinate and other essential metabolites [8]

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Cotinine and nicotine levels were measured in our previous experiment using identical methods, the plasma concentration of nicotine was 222.98 ng/ml, and the plasma cotinine concentration was 376.12 ng/ml ( FIGURE 1 2.4 Behavioral tests Behavioral OF and LD tests were conducted 24 h after the end of each week of cigarette exposure