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44 Additionally, in patients who are already taking some form of oral B 12 supplementation, demonstrating B 12 deficiency can be a challenge, even when symptoms are typical (including those of neuropathy-like paraesthesia and numbness) as serum B 12 concentrations may be just within, or sometimes above, the normal range

In a 32-week phase 2 trial, the effectiveness of cagrilintide paired with semaglutide was compared to either peptide alone in 92 T2D patients

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Dig Dis Sci (2014) 59(11):2693703