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164, S39S45

Intracellular- and extracellular-derived Ca2+ influence phospholipase A(2)-mediated fatty acid release from brain phospholipids

While controlled activation of HIF-1 (e.g., via PHD inhibitors like DMOG) can enhance early healing and angiogenesis, chronic or unregulated activation promotes fibrosis, ECM disorganization, and persistent inflammation (Wu et al., 2018