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Decreased expression of microRNA-29 family in Leomyoma contributes to increased major fibrillar collagen production

In brief, the sections were dewaxed and incubated in Bouins solution overnight at room temperature and then stained with aniline blue and Scarlet to visualize the collagen fibers and nuclei, respectively, under dark conditions at 4 C

Koyama T, Kiyota NBS, Imamura Y,Shibata N,Satake H, Tanaka K,Hayashi H,Onoe T,Asada Y, Yamazaki T, Nose TOS, Nagatani Y

GHK-Cu is also shown to stimulate collagen and elastin, smoothing and firming the skin over time without the potential skin irritation of prescription tretinoin or over-the-counter retinol