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Research by Hayakawa et al

10.1016/j.intimp.2024.113032 60 SakaiS.YamamotoT.TakabatakeY.TakahashiA.Namba-HamanoT.MinamiS.et al (2019)

Since it has a long history of clinical use, its side effects are well known (Pacher et al., 2006)

Nonetheless high-dose N-acetylcysteine therapy acts directly against the reactive oxygen species and NF-B activation in the ER-overload response of the host, independent of viral mutation