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However, prolonged exposure to FFAs hampers glucose-induced insulin secretion and insulin production, potentially resulting in apoptosis-mediated -cell death

Mirzoyan K, Klavins K, Koal T, Gillet M, Marsal D, Denis C, et al

Immunohistochemistry and immunofluorescence techniques confirmed the upregulation of 4HNE, which is a specific end product of ferroptosis, further confirming its involvement in kidney injury, as previously demonstrated (Ide et al., 2021

We did not observe any changes in the UV/Vis absorption spectra of MnO 2 NPs at pH 7.4 or 5.0 over 2 h (Figures 3A,B), indicating that the currently developed MnO 2 NPs are stable at both physiological and lysosomal pH