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For several additional loci, variants were either not present in the available summary statistics or did not reach statistical significance in the external datasets, although some demonstrated directionally consistent effects

Supporting detoxification: Glutathione is involved in the detoxification process, helping to remove toxins and waste products from our body

Although some studies confirm the feasibility of exempting patients who achieve pCR after neoadjuvant systemic therapy under rigorous evaluation using ultrasound or MRI, 323,326,327 this approach is constrained by regional development levels and technological disparities

Despite mixed evidence on statin use and dementia risk 42,43 , our results indicate a possible increased risk with baseline statin use