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Selank Research Protocols & Administration Dosing in Published Research Research investigations have employed various Selank peptide doses depending on species, experimental model, and intended outcome: Rat studies: 300 mcg/kg most common anxiolytic dose (range: 50-500 mcg/kg) Mouse models: 100-300 mcg/kg typical range for behavioral studies Human clinical trials: 0.15-0.6 mg administered intranasally 2-3 times daily Cell culture studies: 1-100 micromolar concentrations for mechanistic investigations Important: These are experimental doses used in specific research contexts and cannot be extrapolated to other species due to profound differences in metabolism, peptide degradation rates, receptor distribution patterns, and pharmacokinetic profiles

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Archives of Otolaryngology-Head and Neck Surgery 133(6):541-45, 2007

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