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Mohan RR, Rodier JT, Sharma A

Evaluation of extraction methods for preparative scale obtention of mangiferin and lupeol from mango peels ( Mangifera indica L.)

This ensures that the vitamins adhere to specific standards and are generally safe to take

In vitro testing on A549 and B16 cell lines identified 8-(pyrrolidin-1-ylmethyl)4-trifluoromethyl ESC as the optimal derivative, demonstrating 20-fold enhanced antiproliferative activity and threefold prolonged half-life in human liver S9, with structural analysis revealing that nitrogen-containing groups at C-8 substantially enhance both metabolic stability and anticancer potency (Pan et al