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Currently, a protein-based vaccine candidate (LVT001) is being tested in a Phase I/II trial as a booster dose in healthy adult volunteers in France (NCT06821126)

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The U373 cells were exposed to a panel of 50 bacterial strains cell-free supernatants, among which Parabacteroides distasonis (MRx0005) and Megasphaera massiliensis (MRx0029) demonstrated significant efficacy in attenuating IL-6 secretion following LPS stimulation