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Contrastingly, polygenic risk scores, amalgamating the effect sizes of numerous variants into a single score, have shown promise in stratifying individuals with and without epilepsy, demonstrating the potential reliability of PRS-based predictions for clinical applications (Khera et al., 2018)

FADS inactivates tumor-intrinsic cGAS-STING pathway to impede CD8 + T cells recruitment To understand how FADS disrupted chemokine signaling and impaired CD8 + T cell recruitment, we investigated the underlying molecular mechanisms