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Premature newborns are more likely to develop BPD, especially those who require mechanical ventilation (Figure 1)

In addition, compared with the therapeutic value of a specific single strain, probiotic consortia containing Lactobacillus reuteri, Lactobacillus gasseri, Lactobacillus acidophilus, and Bifidobacterium lactis were demonstrated to better ameliorate DSS-induced colitis in the mouse model, with their mixed metabolites receiving slightly inferior benefits by comparison with the whole strain [99]

The entire process typically takes about 30-60 minutes, and patients can relax comfortably in our clinic setting during the treatment