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90 ROS overproduction is now recognized as a hallmark of IBD

f , g , Individual tumors (left) and tumor weight (right) of PDX models (CO-04-0070 ( f ) and CO-04-0108 ( g )) treated with different combinatorial regimens

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Surgical Options Surgical intervention is typically saved for more severe Hurley Stage III or refractory stage II cases and ranges in complexity based on the degree and area of tissue involvement and includes: Incision and drainage (not widely encouraged) Punch debridement Unroofing and deroofing debridement Laser therapy Tissue sparing excision Wide excision Key Takeaways Hidradenitis suppurativa is a recurrent chronic inflammatory condition of the folliculopilosebaceous unit Increased incidence in premenopausal females, Black people, smokers, and the obese Always screen patients for depression Weight loss is instrumental in decreasing disease severity Initial treatment includes topical antibiotics and resorcinol Oral antibiotics, resorcinol, hormonal therapies, immunomodulators, and biologics are added for moderate-to-severe disease Surgical treatment is reserved for more severe cases Published December 13, 2021 By Andrew Ross, DO Orthopedic Surgery Resident Join the Conversation Register for Figure 1 and be part of a global community of healthcare professionals gaining medical knowledge, securely sharing real patient cases, and improving outcomes.