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In NAFLD models, Cur reverses the elevated Firmicutes / Bacteroidetes ratio and reduced Akkermansia abundance (Hong et al., 2022), while concurrently upregulating expression of tight junction proteins Occludin and ZO-1, suppressing TLR4/NF-B pathway activation, and reducing LPS exposure, thereby alleviating hepatic inflammation (Hong et al., 2022)

In this study, on the basis of in vivo self-assembly nanotechnology, we designed a PSMA-targeted nano-PROTAC with a proximity degradation effect

doi: 10.1016/j.ejphar.2016.03.063

Because neovascularization makes it easier for the continuously proliferating synovial cells to receive oxygen and nutrients, it hastens the course of osteoarthritis