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Chialva M, di Fossalunga AS, Daghino S, Ghignone S, Bagnaresi P, Chiapello M, et al

Chapter 21, Water soluble vitamins, cobalamin

(1993) investigated IGF-1 LR3 in animal models and demonstrated that its reduced IGFBP binding resulted in enhanced bioactivity compared to native IGF-1 at equivalent doses [2]