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Cited studies are preclinical research, not therapeutic claims

However, the term AKI does not encompass all acute kidney alterations, as these may develop over a longer period than 7 days, substantially impacting medium-term and long-term outcomes

Oral pills are also a viable option, but they rank slightly below sprays in terms of absorption potential

Despite growing documented local associations between opioid prescribing and increased odds of rehospitalization 10,11,12 and emergency department visits 13,14 , Europe currently lacks published opioid stewardship initiatives, such as OEPs