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However, despite the safety and efficacy of the antioxidant therapy, five main factors have hindered its wide acceptance and implementation in the treatment of male infertility: i) lack of randomized placebo-controlled studies that show the safety and efficacy of antioxidants in improving pregnancy rates in infertile couples

E6 recruits E6AP to target p53 for proteasomal degradation, impairing apoptosis and DNA-damage responses

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And while it can be added to the long list of natural products that exert direct antioxidant action, even more, important is beetroot powder's ability to influence cell signaling pathways that activate the body's antioxidant system