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Exposing murine pancreatic -cells to pro-inflammatory cytokines IL-6 and IL-1 led to changes in the cell metallome, especially a decrease in Zn and Ca content and an increase in Fe content, together with changes in the cellular distribution of these metals

[352] It plays a role in regulating intraocular pressure in the eye through its potential complex interaction with nitric oxide, a crucial signaling molecule affecting blood vessel dilation

When combined with SSRIs [selective serotonin reuptake inhibitors] and MAO [monoamine oxidase] inhibitors, it may lead to elevated blood pressure and could induce what is known as serotonin syndrome, said Wolf

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