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410: Prevention, Screening, Diagnosis, and Pregnancy Management for Fetal Neural Tube Defects

Mice studies suggest that inhibiting NNMT stimulates stem cells and boosts muscle repair

5-Amino-1MQ targets the substrate binding site of NNMT the nicotinamide binding pocket competitively inhibiting nicotinamide methylation with an IC50 of 1.2 M under reference assay conditions