glutathione and napqi The molecular mechanisms of acetaminophen-induced hepatotoxicity its potential therapeutic targets 5️⃣ Antidote: NAC (N-acetylcysteine) NAC

5 Antidote: NAC (N acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. Example: Hospitals use NAC as the standard treatment for APAP overdose. Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective PMC Acetaminophen NAPQI Hepatotoxicity: A Cell Line Model System Genome Wide Association Study PMC Unveiling the molecular basis of paracetamol induced hepatotoxicity: Interaction of N acetyl p benzoquinone imine with mitochondrial succinate dehydrogenase ScienceDirect

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