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According to reports, after 24 hours of treatment with celecoxib, an increase in its concentration can enhance the levels of HO-1 mRNA and protein expression in endothelial cells of humans, and the bilirubin content reaches its highest level after 48 hours of celecoxib treatment

This comprehensive model not only advances our understanding of ME/CFSs pathophysiology but also opens new avenues for research and potential therapeutic strategies

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After centrifugation, the supernatant (200 l) was concentrated and resuspended in methanol (100 l)